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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e365b605e6b48d57ab8a5faa0bb64e30d93e280a42fb778faa8b8c6f46f2da4c' 
  AND token = '6+KAA+nf1nhhNGZIUvMUQ6i5OFdpFvL0CychKm5UZEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}