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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c48a6e15d9d4035ad7feae8f3773ef7b1526685877bca2b07d5217a4da0f263c' 
  AND token = 'sOso7tERl2nbt8/Weqad8eOAPQwMiVYWVtgNOYLqspw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}