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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0049080cb65fed1a82a55f44e402e36e00fd9b8c7a100dcedd6a74a291a0df9b' 
  AND token = 'eKyaZhDu61gBvdb3FLs9RQJWgUEQYP3EP5IqydEpifo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}