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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b26ff46d70602c4e6f97e050a69b3a40486c137243a18fe9ef90ecf5519e1491' 
  AND token = 'Baer5HTjgrg9FMzMC2TPLd/oO0FsOaTbBqEsYD0JpE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}