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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '04dfefd146bf2c7b5c59b1e2bf0e290a45671b64baae992d6ed166a347c48087' 
  AND token = '106dxqHc10G7Lle/LxS/8jAQItValdexwCKJtWAu7kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}