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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24fcbc9fe640c7853c9d6781814f9f641e732708a41ae45b427fd87887b01615' 
  AND token = 'WTI5si82b76HuF2xjDhBQwGOGxnvoRs3NE/dd3E8eA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}