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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '371466b94ba72b7af51aa6e3eb0774c57cfb9f29fa0c1fa23ae4cea127496d2e' 
  AND token = '62cQL1PM2MfV2WbhL8QcCxarR1RJha42G84XaUt0Szs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}