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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '540e1ac9a5b64140f8993f4d5818b2fd1a09af133b290ae6d057d8c931f9adc3' 
  AND token = 'xLMJf5gs8lnS9vwxDSYnWbSDjqPPY5raMyp+pzyge8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}