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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2c602072c2cae2216833fe799441d34fd30661638899f8ada6531ee696149d12' 
  AND token = 't3/ShMUWailDN0HFhP8QZALHTrYO6+sEkHYzUQEjdtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}