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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a6285ed0846409cf1718431a4d467217ce45b71c675ff5073e123b0511322f08' 
  AND token = 'w0bFOxzE22kHjOumxI9EBNnhy+76jBwISc2oA25XS5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}