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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a2ba105260665b32889d01024fe7c1e014561a268b49964411e522d11dae2f4' 
  AND token = 'r5HtR00fyS1eEHZ1RLtCmctCNer+Cj0RDN70zcccxz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}