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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2a49c35c3c24a278339db41d8010b9a02c0befe97cba79fcd8168ddb38e8b9c3' 
  AND token = 'hBESQXatLzsuD3y/+XYr0rFnxM0hoJ0neP37SQyup4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}