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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2acd1d135974c5736db837be1857bf2ca7bebd8bcafde3657a998bfa6db79c53' 
  AND token = 'QCM2CrcYbIhpKgk5sDSfLa/58kadPFouIDscKPw+x/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}