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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fc66fe774cfb93e5ec4127d7ca4224a99900d87c5d227da19ac1959e774cb7af' 
  AND token = 'JYyFaqZxq0VZaiClVpcVgQrEuGgWF29TVMVfiOAM60o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}