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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c24166a6f6283ecb107739d01e7ba31a5b5ee85ce8625e77b953e9e9b554c4f3' 
  AND token = 'JKH5a5SZzmrMQvSazvUoY7+kGt8KaoXziZT4KP1bSGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}