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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd391fdedc8801d6335c4960c80e56601b50505b608fd2d139a570c42ff2bf269' 
  AND token = 'O1X71ztfyU3KSkLA7tmLf49gDv9rvFQ09UkHXrB7Ef4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}