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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd250aaaf8988c50a9926348b3d35285fdda2659f1e5fd76f7c16f31d1a5cca95' 
  AND token = 'bCpxygKriwm2fBa8fONv9qKknEpGzrcsiEpcBe7RDc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}