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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1854697a45d17612b04c2867e2aaf54885523cb1734d35d35c177fc2f826f2e4' 
  AND token = '1OANPepzrD81GP0oQsR65lNEG92+3QyfGupnB++vV54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}