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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8857cc44fa8eae687f69d1c01d62f02b6cbe1163e3c4e21dd7e373437c06413b' 
  AND token = 'fZayJ68fp+v9t6AnPsHX9YBBAN2fer/NLNSaUAomlL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}