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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cc6adebbf71c0b0aaca0b63d3c336060dcd1ad7230e7464c26e61082349c0510' 
  AND token = 'T2iPckKIFxgwS+zXB9auRxTAfkrrytkJU3wmF+ZgYGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}