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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2bb34302e65c93e17592fdaffe544671a725ea7d4f273384c52dca3639b181b7' 
  AND token = 'XSiv+u45dKbtboVFFlse8qNOXF6RNDLI5MxkkVxngN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}