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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2282330b3cc24b750a90004004f45f9b503ac87e6d7a997ff15da92e1ef1d827' 
  AND token = 'qjLInopo8qERMhi1yOFjucQQ2sP3XMVjHm4uIDGRlDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}