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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a428839579d03c1770bcfb8e2596f186bbbd797df237b083c56c96aa540b63b0' 
  AND token = 'UwX76vHzzgCNs7fjA6apU6fNa27HCH84mg7S3TzG1TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}