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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '17d49d50018b7eff7006a3eec2c504f08a5d0761d29e600c46b4eaaf036876b0' 
  AND token = 'w6BlD8Vlo2qQ7xdb73GumkXLZaK97JhdFmuwJEbiy2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}