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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42db66fe1a7ff2e2dfffe403af4f9a766f42bfb4fc5bb909d7978893c15d1fb9' 
  AND token = 's7/S9nGVk0ke7VN/CG8HFYXVZGiyAwKO6aLbuLDG6aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}