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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b0c542f40da319ac2eceaeeff5dff2f7522ef45c80de6dc817c462095c5a0def' 
  AND token = 'GPQTIWANfcfEpwHzSvFF+BGrzrck9nRcEvILjo7Efu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}