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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd80d39448ac70ee8e8daed9f8ecc371e6ae0683d1159e22aabc51944d05abd45' 
  AND token = 'eK2AAwJ2i26Cb0iBJX2hHQSCDZ8fYasuj6394BIyeQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}