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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '323f8b104543860824fb315c5267f02f2e4a67775877356e71a184ddba72c492' 
  AND token = '0riO7GTBkQm2MCpY4FVn81ensjs3ptg1UEjM4ymlfag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}