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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e134e712cca21865cd82eae0509fba1be3e1bd3288d0b0329e8b325d74241a3d' 
  AND token = 'pxeLMD/DJ/GmSXQtG8r4L6z0wPgWocgHYGtOxS7DSnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}