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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7069cd1b607be840f113c143be68360b0b3b03887018d41a1098a65ea2a82f16' 
  AND token = 'd9LH9JLO2o2s1XMMRwueM63t8EeuT+AxHePJxs4vbaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}