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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a57d3b07a5853f9e3419c74898e62269f11bfff67a7a56801e96bd8b9b179e9' 
  AND token = 'TzFASWxaa6TV94CEdGn0aisaxg01EcwMdkGvebBcHmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}