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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5241b2a976098bdd2c06b8c3367dcb1985df01e672b9cbf6cbd0d20c66a15153' 
  AND token = 'x0xKUSzvJq0ZGKoh56rI7mxs859JY7L0U9o76hLnlnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}