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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b72c414dde73d51145492ee5e091c362d1b1e724998e9d7131c1e366afd6550f' 
  AND token = 'VPLJ1MoAHOSrFefS4EzfTPDcOuJBjXCIyKWo7TjZPss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}