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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '52b4384307a502a940b1ee9f3f735a1049eee22adc71dca0e2613223e3c80c88' 
  AND token = 'RE6RiVQ/sdVSziiBpNybG3AsPfUpo8AhQiC3TnVV5Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}