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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66bdd8707f4b56189a62f9d2c382e9e4cdf9139589a9d64ea6641cfeb90b135b' 
  AND token = 'tzwVOEoPkDeHM4M6EYBmtiAN5bs50dMDqTeuBldFWkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}