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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e19440f0c8ab2417642c1c35b451b1c3d86937fcf553964e4179cd482d58b1f' 
  AND token = 'p5OdfAAl3lR7W/YicaoLrMqkCDTVWhaT+TCOrYgp65s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}