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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4881bec48fa2ae9309914b383cb4cb857829ed711d49fedf3bf27c283d81d2f7' 
  AND token = '6zYOn88tBxGoEuTKcslPYxpkSoGoMVbl21KVWHiU5Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}