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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5326304a6197ae6b34b41e893206b00e51b1b394592305b86737334bc412dde' 
  AND token = 'T4i0UmUKqcSBBjL+cDzlT3hb4fqN1hFq440zl1RjdLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}