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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b5973482677390aef9a12564f09d0b69e2497d038053193392450c2c7be55fa' 
  AND token = 'z0GZPcft77bmBZUd33hJTaDoRSN6LwvcAtJkczTS7IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}