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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a4666eb70fff67f0f23066387db152180dc45bbf89dc0aade6a355baee1a03f8' 
  AND token = 'fkND8Lzc9PD1VXWxgfTQlHp8AdxivgD22ZYGVhXWaoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}