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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '99e9859dc863b18e9f4203ef07818e3fa73d6c907be5c5a57c1ea9787815147a' 
  AND token = 'MW21QtEx6YCLHkuWQ8hQSYpJ1CDLnIu29SWCAL7tjCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}