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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '84c59eb06a0d109031a1d99bd7f15891546d78d531953a6f0be70f6d357ad212' 
  AND token = '2f1v4xqxSf1dqOjoGgI7+G6cw4vGSVMS16RmVNoyOUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}