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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7a5e8bea7f214cf498b8f7e34380844ae1389ac309c4710c6d36bc7f1644fc48' 
  AND token = 'D9sIDJQghreUM64GdU4Tr3YJnNzX5m/VTZ9OsVYmJrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}