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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f4d33e3a647758c2c0304f422bf03207490af8b66b34865ed00787e3996c51d6' 
  AND token = 'ed4MJeCg22uG+anR5bGWlG20IDNYBSicbjEf9Pl7Uds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}