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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '44281388f4fb37973e5ff0666f797a81da3ceb27ce49568588fe265c356e7152' 
  AND token = 'N+uXHpfPSDNbnxS9mS7UG2s3rCp1dj2Snlp/j7L06zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}