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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd143500dc47fd65cab3a57cf9aa388db2ad2a73f26db75f02f7963693ef21a43' 
  AND token = 'f+TQmqx5p0f/6qZeFpbH+m3Lw7hE9v48IkUrs4jOEfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}