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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b80b7584dbb519439ae2b15211e01eb3c6ccc4fb456a7a3e9064d920ebf4d3f' 
  AND token = 'flyG1Pfx7jhcjsH+2mCkrCCDXEHyQwgMv4NfM0eRkh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}