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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8270623bb6665ba4c9eb20d7b98972fb01ddc774f12a7bfd39fd961c37a0c770' 
  AND token = 'UfR8hT7J4h8GDiCqYt2LzYUrmMdRWuNCqPt4icaxoXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}