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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6f5669fff28db5b7e5132d103a43af4e509f4ee7a45ec4b15117e65d54002c41' 
  AND token = 'mANMLNBfAAqpkQdkxhJEzYsLzZn0HxfOAmJDf6lOUD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}