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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '81de1003d31c38e555408dc441309ade134cd619d82036c44a1b114b988192f5' 
  AND token = 'EX942MpqvQ94plF8nJH3aycyfVfTX8yviwymGuFIhHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}